Aristotelesstraat 18, 1064 LD, Amsterdam
Street Victor Brauner no. 400, Bl. 1, Ap. 13, District 3, Bucharest, Romania
+31 (0) 629075858
info@regpakbiopharma.com
PRODUCT AUTHORISATION / MAINTENANCE

Consistency with global application procedures

It is important to understand and define the clear regulatory strategy by considering the target markets/ regions, different patent terms and their extension, various application possibilities, data requirements, deadlines for launching products to be marketed in different markets/ regions. Marketing authorisations for medicinal products are subject to very strict overall requirements. Preparing, submitting, and maintaining CTD/eCTD dossiers places considerable demands on a company’s human resources.

Our services include

Regulatory Strategy & due diligence: Biologicals, Biosimilars, Gene & Stem Cell Therapy, Vaccines, Small/Large Molecules, Controlled DS including CBD, Generics
Liaison with regulatory agencies
Marketing Authorisation/MA Transfer/ Maintenance:​ Variations-CMC and Safety​ Renewals of MAs​ Sunset clause extension(EU)
Scientific advice
Global regulatory intelligence
Orphan Drug Designation
Early access to unapproved medicinal products
Preparation of pricing and reimbursement to EU/ Non-EU regulatory authorities
Electronic submission of product information to EMA database (XEVMPD )
Local regulatory support/local representatives in EU

Product Literature and Readability Testing

Good quality product literature is one of the keys to successful regulatory approval and attention to detail is important in writing the Summaries of Product Characteristics, Patient Information Leaflets and labelling texts. RegPak BioPharma Consulting can advise on the regulatory requirements for both content and format under EU or non-EU legislation as well as write or review the relevant texts. Leaflets intended for the patient must be written in plain English and there is now a requirement in Europe for these to be user tested to ensure readability. RegPak BioPharma Consulting can arrange a full readability testing service and can prepare test reports suitable for submission.

NUTRITIONAL & FOOD SUPPLEMENT

We provide comprehensive scientific, technical, regulatory, legal, and project management services Nutraceuticals are food or food ingredients that have defined physiological effects. They do not easily fall into the legal categories of food or drug and often inhabit a grey area between the two. These products in general terms cover health promotion, “optimal nutrition” the concept of enhanced performance – both physically and mentally – and reduction of disease risk factors. On the other hand, a dietary supplement, also known as food supplement or nutritional supplement, is a preparation intended to supply nutrients, such as vitamins, minerals, fatty acids or amino acids, that are missing or are not consumed in sufficient quantity in a person's diet. Some countries define dietary supplements as foods, while in others they are defined as drugs. RegPak BioPharma Consulting provides expert opinion and advice in the areas of technology evaluation / due diligence in nutraceuticals and food supplement product approval. We perform a comprehensive document review and prepare a written opinion as to the potential for success for the approach (es). Our services include:

  • Nutraceutical Product Approval
  • Food Supplement Approval
  • Novel Food Application

COSMETICS

Cosmetic products are topical products that are not classified as a medicinal product. Cosmetic products are also important consumer products: apart from "traditional" cosmetic products, such as make-up and perfumes, it also includes products for personal hygiene, for example tooth-care products, shampoos and soaps. There is a main regulatory framework which aims at ensuring the free circulation of cosmetic products in the internal market and safeguarding the safety of cosmetic products placed on the EU-market. RegPak BioPharma Consulting can assist you in bringing your cosmetic products, including products with therapeutic value, to the market shelf by:

  • Notifying appropriate Regulatory Authorities
  • Drafting consumer labeling
  • Package design and outer labelling
Regulatory Writing
    • Clinical Development Plans (CDPs)
    • Clinical Study Protocol (CSP)
    • Investigators Brochure (IB)
    • Pediatric Investigational Plans (PIP)
    • Orphan Drug Applications
    • Target Product Profile (TPP)
    • Reports required for EFSA Applications
    • Environmental Risk Assessment (ERA)​
    • Prevalence & Epidemiology Reports
MA Holding:
  • Opportunity for companies to use RegPak as applicant and Marketing Authorization Holder for EU.
  • Performing all communication with regulatory authorities.

FOR MORE INFO CONTACT US!

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OUR EXPERTISE
We deal in:
  • Summary of Product Characteristics incl. company core data sheet (SmPC or CCDS )
  • Patient Information Leaflet (PIL)
  • Labelling Texts 
  • Mock-ups preparation and updates Readability Testing 
  • Translation of product information text (and harmonization for generics)
MA Holding:
  • Opportunity for companies to use RegPak as applicant and            Marketing Authorization Holder for EU.
  • Performing all communication with regulatory authorities.